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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTY2D1
All Species:
12.73
Human Site:
S551
Identified Species:
23.33
UniProt:
Q68D10
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68D10
NP_919261.2
685
75546
S551
S
K
N
I
I
S
R
S
S
N
G
Q
M
N
G
Chimpanzee
Pan troglodytes
XP_508321
684
75407
S551
S
K
N
I
I
S
R
S
S
N
G
Q
M
N
G
Rhesus Macaque
Macaca mulatta
XP_001082108
684
75599
S551
S
K
N
I
I
S
R
S
S
N
G
Q
M
N
G
Dog
Lupus familis
XP_534086
793
86791
N662
N
I
I
S
R
S
S
N
G
Q
M
N
G
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q68FG3
682
74799
S551
K
N
I
I
S
R
S
S
N
G
Q
I
N
G
M
Rat
Rattus norvegicus
XP_002725626
681
74519
S551
K
N
I
I
S
R
S
S
N
G
Q
M
N
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517926
644
69600
P509
S
K
N
I
V
A
R
P
G
P
G
R
M
N
G
Chicken
Gallus gallus
XP_421015
633
66869
A506
R
P
G
V
G
P
S
A
G
P
G
R
P
G
S
Frog
Xenopus laevis
Q6NU13
800
83727
F660
E
T
I
S
S
K
N
F
V
P
K
S
I
N
G
Zebra Danio
Brachydanio rerio
Q6DGN6
629
69420
S513
P
R
T
V
I
G
P
S
G
H
R
I
L
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMP6
581
65683
R472
P
P
A
D
V
K
R
R
K
P
N
E
P
P
V
Honey Bee
Apis mellifera
XP_395689
579
67372
K470
V
P
H
L
R
E
Q
K
K
S
F
I
N
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793115
639
72247
R504
P
R
L
V
N
H
D
R
E
R
P
R
P
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
73.6
N.A.
80.5
82.1
N.A.
55.6
47.8
43
42.7
N.A.
28.3
23.2
N.A.
24
Protein Similarity:
100
99.5
98.5
78.8
N.A.
89.9
90.3
N.A.
66.5
58
56.6
58.6
N.A.
44.2
41.6
N.A.
39.8
P-Site Identity:
100
100
100
6.6
N.A.
13.3
13.3
N.A.
60
6.6
13.3
13.3
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
20
20
N.A.
80
26.6
20
40
N.A.
20
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
8
0
8
8
0
0
31
16
39
0
8
24
39
% G
% His:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
31
47
31
0
0
0
0
0
0
24
8
0
0
% I
% Lys:
16
31
0
0
0
16
0
8
16
0
8
0
0
0
24
% K
% Leu:
0
0
8
8
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
8
31
8
16
% M
% Asn:
8
16
31
0
8
0
8
8
16
24
8
8
24
47
0
% N
% Pro:
24
24
0
0
0
8
8
8
0
31
8
0
24
8
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
8
16
24
0
0
0
% Q
% Arg:
8
16
0
0
16
16
39
16
0
8
8
24
0
0
0
% R
% Ser:
31
0
0
16
24
31
31
47
24
8
0
8
0
8
8
% S
% Thr:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
24
16
0
0
0
8
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _